RSICC CODE PACKAGE CCC-720
1. NAME AND TITLE
INDOSE V2.1.1: Internal Dosimetry Code System Using Biokinetics Models.
2. CONTRIBUTORS
Soreq -Nuclear Research Center, Yavne, Israel, through the OECD NEA Data Bank, Issy-les-Moulineaux, France.
3. CODING LANGUAGE AND COMPUTER
Fortran 90; Intel PC - Windows or Linux (C00720PC58600).
[Executables only; no source.]
4. NATURE OF PROBLEM SOLVED
InDose is an internal dosimetry code to calculate dose estimations using biokinetic models (presented in ICRP-56 to ICRP71) as well as older ones. The code uses the ICRP-66 respiratory tract model and the ICRP-30 gastrointestinal tract model as well as the new and old biokinetic models. The code was written in such a way that the user can change any parameters of any one of the models without recompiling the code. All parameters are given in well annotated parameters files that the user may change. As default, these files contain the values listed in ICRP publications.
The full InDose code was planned to have three parts: 1) the main part includes the uptake and systemic models and is used to calculate the activities in the body tissues and excretion as a function of time for a given intake. 2) An optimization module for automatic estimation of the intake for a specific exposure case. 3) A module to calculate the dose due to the estimated intake. Currently, the code is able to perform only it`s main task (part 1) while the other two have to be done externally using other tools. In the future, developers would like to add these modules in order to provide a complete solution.
The code was tested extensively to verify accuracy of its results. The verification procedure was divided into three parts: 1) verification of the implementation of each model, 2) verification of the integrity of the whole code, and 3) usability test. The first two parts consisted of comparing results obtained with InDose to published results for the same cases. For example ICRP-78 monitoring data. The last part consisted of participating in the 3rd EIE-IDA and assessing some of the scenarios provided in this exercise. These tests where presented in a few publications. Good agreement was found between the results of InDose and published data.
5. METHOD OF SOLUTION
InDose employs the ``LSODES'' algorithm to solve the set of stiff differential equations that describe the models mathematically. This is a well known algorithm for differential equations that can deal with very stiff problems and account accurately for both the fast and slow processes. The version used is specially designed for sparse matrix (i.e., when most of the coefficients in the equations are zero as happens here) and uses this fact to lower memory requirements.
The new biokinetic models were implemented in InDose using a generalized form that can be applied to any of the new biokinetic models and even to the older Iodine model presented in ICRP-30. It is also expected to be applicable to any new biokinetic model that the ICRP might present in the future. A new model for existing and/or new element (element which is not yet in the database) can be added by simply writing a model parameters file for it.
6. RESTRICTIONS OR LIMITATIONS
Fortran source files are not included in this package, so the code can only be run under Windows or Linux using included executables.
7. TYPICAL RUNNING TIME
The Cs-137 test case ran in a few seconds on a Pentium IV 1.6MHz.
8. COMPUTER HARDWARE REQUIREMENTS
InDose runs only on Personal Computers.
9. COMPUTER SOFTWARE REQUIREMENTS
The Fortran 90 source is not included in this package; included executables run under Windows or Linux. PLT2TXT is included in the package to translate binary plot files to column-wise format. On MS Windows machines, InDose was compiled by the author using Digital Fortran 5. RSICC tested on the following systems with the distributed executables.
10. REFERENCE
I. Silverman, "InDose User Manual," SNRC 2979 (December 1999).
11. CONTENTS OF CODE PACKAGE
Included are the referenced document on a CD which also contains the executables, test cases, and data files in a GNU compressed tar file and in a self-extracting Windows file. No source files are included.
12. DATE OF ABSTRACT
November 2003.
KEYWORDS: INTERNAL DOSE; RADIONUCLIDES.